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The goal is to understand patterns: what happens after dose day, what foods feel better or worse, whether you are eating enough protein, whether water or fiber affects constipation, and what you should bring up with your clinician
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Orforglipron has shown weight-loss and risk-factor effects, but adjudicated cardiovascular outcome data are needed before it can be positioned alongside semaglutide 2.4 mg for cardiovascular risk reduction in established CVD (25, 26)